handling may be a different story though!
It is a mixed package, and yes, many cars are one-trick ponies. Although people like Sidious may vehemently object to comparing a Japanese saloon to the holiest of untouchable holy cars (mid-engine uber-expensive cars), the fact is that the reputation of the GT-R is that it is frankly the only Japanese car, virtually the ONLY car for the masses, that can be tuned on all levels (acceleration, deceleration, handling) to challenge the highest performance production cars made. (NSX you say? Try making 600bhp out of one, then compare how much you spent compared to making 600bhp out of a Skyline. Getting big power of the NSX has always been the one problem keeping that car from being the end all be all of Japanese performance).
We'll set aside the Bugatti Veyron (also a one-trick pony, a stage 1 GT-R will beat it around the Nurburgring with little difficulty) as well as specialty cars like the Radical.
I submit that the hypercar category really only consists of three cars (in order): the Porsche Carrera GT, the Ferrari Enzo, and the McLaren F1. Only these three cars really put everything together - extreme top speed, great chassis, and superb handling (the F40 really ought to be in there, but in this day and age its acceleration is, and this is obviously relative, slow).
The R35 is really putting the pressure on the Carrera GT and the V-spec will likely surpass it. An 800bhp Skyline GT-R will easily outrun one, an Enzo as well.
But where the Skyline fails is in top speed. The gearing isn't high enough. Eventually, given enough road, a stock-geared GT-R, even with 1200bhp, will slowly but surely get passed.
I think I can say with little argument that no street car, regardless of tuning, can definitively beat the McLaren F1. It's an MX-5 with 600+bhp ffs!
Ferrari does indeed have a thorough racing pedigree. So why is it that their races (as cited above) are single-make? There's no excuse - the Enzo must post a Nurburgring time - the now de facto standard.
And...probably in August when my car has been run in, I have made some friendly arrangements to video my car with other like-minded exotic sports car owners, including an Enzo (this one owned by a VERY nice guy, he also owns the first R35 to enter Korea, tuned by Amuse to about 500+bhp, and respects all sports cars regardless of manufacturer). I'll try to get some of the footage of my car running against his Enzo, put some speculation to rest and see what a mid-power GT-R can do

2 bars boost and a 9000rpm redline, I expect to do well against the Carrera GT however - provided I don't drive ham-fisted and with two left feet!!